RNA Details
Disease Name
myocardial infarction
Tissue
heart
RNA Symbol
mir-3185
RNA ID
RNA Type
miRNA
Alteration Pattern
up regulation
Species
homo sapiens
Detection Methods
qRT-PCR;western blot;MTT and EdU assays etc.
Target
MHRT
Pathway
TGF-BETA SIGNALING PATHWAY
PubMed ID
Title
LncRNA MHRT Promotes Cardiac Fibrosis via miR-3185 Pathway Following Myocardial Infarction
Year
2021
Function
Overexpression of miR-3185 inhibited the upregulation of Col I and Col III induced by TGF-beta1.MHRT promoted cardiac fibrosis after MI through miR-3185 and increased myocardial collagen deposition and promoted myocardial fibrosis.